Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8(+) T lymphocyte proliferation

Two major phospholipase D (PLD) isozymes in mammals, PLD1 and PLD2, hydrolyze the membrane phospholipid phosphatidylcholine to choline and the lipid messenger phosphatidic acid. Although their roles in cancer cells have been well studied, their functions in tumor microenvironment have not yet been c...

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Detalles Bibliográficos
Autores principales: Ngo Thai Bich, Van, Hongu, Tsunaki, Miura, Yuki, Katagiri, Naohiro, Ohbayashi, Norihiko, Yamashita-Kanemaru, Yumi, Shibuya, Akira, Funakoshi, Yuji, Kanaho, Yasunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908902/
https://www.ncbi.nlm.nih.gov/pubmed/29674728
http://dx.doi.org/10.1038/s41598-018-24512-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908902/
https://www.ncbi.nlm.nih.gov/pubmed/29674728
http://dx.doi.org/10.1038/s41598-018-24512-x

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