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Detecting phenotype-driven transitions in regulatory network structure
Complex traits and diseases like human height or cancer are often not caused by a single mutation or genetic variant, but instead arise from functional changes in the underlying molecular network. Biological networks are known to be highly modular and contain dense “communities” of genes that carry...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908977/ https://www.ncbi.nlm.nih.gov/pubmed/29707235 http://dx.doi.org/10.1038/s41540-018-0052-5 |