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Antibody Repertoires Identify β-Tubulin as a Host Protective Parasite Antigen in Mice Infected With Trypanosoma cruzi

Few studies investigate the major protein antigens targeted by the antibody diversity of infected mice with Trypanosoma cruzi. To detect global IgG antibody specificities, sera from infected mice were immunoblotted against whole T. cruzi extracts. By proteomic analysis, we were able to identify the...

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Detalles Bibliográficos
Autores principales: Montalvão, Fabricio, Nascimento, Danielle Oliveira, Nunes, Marise P., Koeller, Carolina M., Morrot, Alexandre, Lery, Leticia Miranda S., Bisch, Paulo M., Teixeira, Santuza M. R., Vasconcellos, Rita, Freire-de-Lima, Leonardo, Lopes, Marcela F., Heise, Norton, DosReis, George A., Freire-de-Lima, Célio Geraldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909033/
https://www.ncbi.nlm.nih.gov/pubmed/29706955
http://dx.doi.org/10.3389/fimmu.2018.00671