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Loss of Zbtb32 in NOD mice does not significantly alter T cell responses.

Background : We previously identified the transcriptional regulator Zbtb32 as a factor that can promote T cell tolerance in the Non-Obese Diabetic (NOD) mouse, a model of Type 1 diabetes. Antigen targeted to DCIR2 (+) dendritic cells (DCs) in vivo inhibited both diabetes and effector T cell expansio...

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Detalles Bibliográficos
Autores principales: Coley, William D., Zhao, Yongge, Benck, Charles J., Liu, Yi, Hotta-Iwamura, Chie, Rahman, M. Jubayer, Tarbell, Kristin V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909056/
https://www.ncbi.nlm.nih.gov/pubmed/29707204
http://dx.doi.org/10.12688/f1000research.13864.2