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Loss of Zbtb32 in NOD mice does not significantly alter T cell responses.
Background : We previously identified the transcriptional regulator Zbtb32 as a factor that can promote T cell tolerance in the Non-Obese Diabetic (NOD) mouse, a model of Type 1 diabetes. Antigen targeted to DCIR2 (+) dendritic cells (DCs) in vivo inhibited both diabetes and effector T cell expansio...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000 Research Limited
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909056/ https://www.ncbi.nlm.nih.gov/pubmed/29707204 http://dx.doi.org/10.12688/f1000research.13864.2 |