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Heavy Metal-Induced Expression of PcaA Provides Cadmium Tolerance to Aspergillus fumigatus and Supports Its Virulence in the Galleria mellonella Model

Most of the metal transporters in Aspergillus fumigatus are yet uncharacterized. Their role in fungal metabolism and virulence remains unclear. This paper describes the novel PIB-type cation ATPase PcaA, which links metal homeostasis and heavy metal tolerance in the opportunistic human pathogen A. f...

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Detalles Bibliográficos
Autores principales: Bakti, Fruzsina, Sasse, Christoph, Heinekamp, Thorsten, Pócsi, István, Braus, Gerhard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909057/
https://www.ncbi.nlm.nih.gov/pubmed/29706948
http://dx.doi.org/10.3389/fmicb.2018.00744