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Structure activity relationship (SAR) and quantitative structure activity relationship (QSAR) studies showed plant flavonoids as potential inhibitors of dengue NS2B-NS3 protease

BACKGROUND: Due to dengue virus disease, half of the world population is at severe health risk. Viral encoded NS2B-NS3 protease complex causes cleavage in the nonstructural region of the viral polyprotein. The cleavage is essentially required for fully functional viral protein. It has already been r...

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Detalles Bibliográficos
Autores principales: Sarwar, Muhammad Waseem, Riaz, Adeel, Dilshad, Syed Muhammad Raihan, Al-Qahtani, Ahmed, Nawaz-Ul-Rehman, Muhammad Shah, Mubin, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909242/
https://www.ncbi.nlm.nih.gov/pubmed/29673347
http://dx.doi.org/10.1186/s12900-018-0084-5