A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data

BACKGROUND: Detailed modelling of the neutral mutational process in cancer cells is crucial for identifying driver mutations and understanding the mutational mechanisms that act during cancer development. The neutral mutational process is very complex: whole-genome analyses have revealed that the mu...

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Detalles Bibliográficos
Autores principales: Bertl, Johanna, Guo, Qianyun, Juul, Malene, Besenbacher, Søren, Nielsen, Morten Muhlig, Hornshøj, Henrik, Pedersen, Jakob Skou, Hobolth, Asger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909259/
https://www.ncbi.nlm.nih.gov/pubmed/29673314
http://dx.doi.org/10.1186/s12859-018-2141-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909259/
https://www.ncbi.nlm.nih.gov/pubmed/29673314
http://dx.doi.org/10.1186/s12859-018-2141-2

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