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A catalytic highly enantioselective allene approach to oxazolines

Oxazolines are a very important class of heterocyclic compounds. However, catalytic enantioselective syntheses are very limited. Here, a highly enantioselective palladium-catalyzed coupling-cyclization of readily available N-(buta-2,3-dienyl) amides with aryl or 1-alkenyl iodides has been developed...

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Detalles Bibliográficos
Autores principales: Luo, Hongwen, Yang, Zheng, Lin, Weilong, Zheng, Yangguangyan, Ma, Shengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909368/
https://www.ncbi.nlm.nih.gov/pubmed/29732113
http://dx.doi.org/10.1039/c7sc04079b