Histone deacetylase inhibitor-based chromatin precipitation for identification of targeted genomic loci

Histone deacetylase (HDAC) catalyzes the removal of acetyl marks from histones, effectively regulating gene expression. Genome wide chromatin immunoprecipitation (ChIP) studies have shown HDACs are present on numerous active and repressed genes. However, HDAC inhibitors (HDACi) only regulate a small...

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Detalles Bibliográficos
Autores principales: Hanigan, Thomas W., Danes, Jeanne M., Taha, Taha Y., Frasor, Jonna, Petukhov, Pavel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Biological Methods 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909381/
https://www.ncbi.nlm.nih.gov/pubmed/29682593
http://dx.doi.org/10.14440/jbm.2018.216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909381/
https://www.ncbi.nlm.nih.gov/pubmed/29682593
http://dx.doi.org/10.14440/jbm.2018.216

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