Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1

SKI is a transcriptional co-regulator and overexpressed in various human tumors, for example in acute myeloid leukemia (AML). SKI contributes to the origin and maintenance of the leukemic phenotype. Here, we use ChIP-seq and RNA-seq analysis to identify the epigenetic alterations induced by SKI over...

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Detalles Bibliográficos
Autores principales: Feld, Christine, Sahu, Peeyush, Frech, Miriam, Finkernagel, Florian, Nist, Andrea, Stiewe, Thorsten, Bauer, Uta-Maria, Neubauer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909421/
https://www.ncbi.nlm.nih.gov/pubmed/29471413
http://dx.doi.org/10.1093/nar/gky119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909421/
https://www.ncbi.nlm.nih.gov/pubmed/29471413
http://dx.doi.org/10.1093/nar/gky119

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