Cargando…

Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1

SKI is a transcriptional co-regulator and overexpressed in various human tumors, for example in acute myeloid leukemia (AML). SKI contributes to the origin and maintenance of the leukemic phenotype. Here, we use ChIP-seq and RNA-seq analysis to identify the epigenetic alterations induced by SKI over...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feld, Christine, Sahu, Peeyush, Frech, Miriam, Finkernagel, Florian, Nist, Andrea, Stiewe, Thorsten, Bauer, Uta-Maria, Neubauer, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909421/ https://www.ncbi.nlm.nih.gov/pubmed/29471413 http://dx.doi.org/10.1093/nar/gky119

Ejemplares similares

ChIPing the cistrome of PXR in mouse liver
por: Cui, Julia Yue, et al.
Publicado: (2010)

Sea-ATI unravels novel vocabularies of plant active cistrome
por: Wen, Chenjin, et al.
Publicado: (2023)

Notch-dependent and -independent functions of transcription factor RBPJ
por: Friedrich, Tobias, et al.
Publicado: (2022)

Tumor-suppressive disruption of cancer subtype-associated super enhancer circuits by small molecule treatment
por: Koeniger, Anke, et al.
Publicado: (2023)

The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages
por: Daniel, Bence, et al.
Publicado: (2018)

Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-κB cistrome to reprogram the prostate cancer cell transcriptome
por: Malinen, Marjo, et al.
Publicado: (2017)

Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
por: Xu, Chenxi, et al.
Publicado: (2021)

Distinct CoREST complexes act in a cell-type-specific manner
por: Mačinković, Igor, et al.
Publicado: (2019)

HDAC3 functions as a positive regulator in Notch signal transduction
por: Ferrante, Francesca, et al.
Publicado: (2020)

Mechanism of promoter repression by Lac repressor–DNA loops
por: Becker, Nicole A., et al.
Publicado: (2013)

Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response
por: Giaimo, Benedetto Daniele, et al.
Publicado: (2018)

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
por: Weber, Lisa Marie, et al.
Publicado: (2022)

FRET studies of a landscape of Lac repressor-mediated DNA loops
por: Haeusler, Aaron R., et al.
Publicado: (2012)

A bistable hysteretic switch in an activator–repressor regulated restriction–modification system
por: Williams, Kristen, et al.
Publicado: (2013)

Repressor activity of the RpoS/σ(S)-dependent RNA polymerase requires DNA binding
por: Lévi-Meyrueis, Corinne, et al.
Publicado: (2015)

Transcriptional repressor NIR interacts with the p53-inhibiting ubiquitin ligase MDM2
por: Heyne, Kristina, et al.
Publicado: (2014)

The mechanism and high-free-energy transition state of lac repressor–lac operator interaction
por: Sengupta, Rituparna, et al.
Publicado: (2017)

Repressor CopG prevents access of RNA polymerase to promoter and actively dissociates open complexes
por: Hernández-Arriaga, Ana M., et al.
Publicado: (2009)

Genome-wide gene regulation of biosynthesis and energy generation by a novel transcriptional repressor in Geobacter species
por: Ueki, Toshiyuki, et al.
Publicado: (2010)

Arabidopsis DNA polymerase ϵ recruits components of Polycomb repressor complex to mediate epigenetic gene silencing
por: del Olmo, Iván, et al.
Publicado: (2016)

Sliding of a single lac repressor protein along DNA is tuned by DNA sequence and molecular switching
por: Tempestini, Alessia, et al.
Publicado: (2018)

Regulation of alginate catabolism involves a GntR family repressor in the marine flavobacterium Zobellia galactanivorans Dsij(T)
por: Dudek, Magda, et al.
Publicado: (2020)

The transcriptional repressors VAL1 and VAL2 recruit PRC2 for genome-wide Polycomb silencing in Arabidopsis
por: Yuan, Liangbing, et al.
Publicado: (2020)

Novel function of the unique N-terminal region of RUNX1c in B cell growth regulation
por: Brady, Gareth, et al.
Publicado: (2013)

The transcriptional co-repressor TLE3 suppresses basal signaling on a subset of estrogen receptor α target genes
por: Jangal, Maïka, et al.
Publicado: (2014)

Single molecule analysis of DNA wrapping and looping by a circular 14mer wheel of the bacteriophage 186 CI repressor
por: Wang, Haowei, et al.
Publicado: (2013)

The global repressor FliZ antagonizes gene expression by σ(S)-containing RNA polymerase due to overlapping DNA binding specificity
por: Pesavento, Christina, et al.
Publicado: (2012)

Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control
por: Szabó, Judit E., et al.
Publicado: (2014)

Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA
por: Cui, Huanhuan, et al.
Publicado: (2016)

The Krüppel-associated box repressor domain induces reversible and irreversible regulation of endogenous mouse genes by mediating different chromatin states
por: Ying, Yue, et al.
Publicado: (2015)

Time-resolved assembly of a nucleoprotein complex between Shigella flexneri virF promoter and its transcriptional repressor H-NS
por: Ulissi, Ulisse, et al.
Publicado: (2014)

Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation
por: Debaize, Lydie, et al.
Publicado: (2018)

RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth
por: Gunnell, Andrea, et al.
Publicado: (2016)

Recruitment of the ATP-dependent chromatin remodeler dMi-2 to the transcribed region of active heat shock genes
por: Mathieu, Eve-Lyne, et al.
Publicado: (2012)

Zur and zinc increase expression of E. coli ribosomal protein L31 through RNA-mediated repression of the repressor L31p
por: Rasmussen, Rebecca A, et al.
Publicado: (2022)

A SUMO-regulated activation function controls synergy of c-Myb through a repressor–activator switch leading to differential p300 recruitment
por: Molværsmyr, Ann-Kristin, et al.
Publicado: (2010)

Bacteriophage GIL01 gp7 interacts with host LexA repressor to enhance DNA binding and inhibit RecA-mediated auto-cleavage
por: Fornelos, Nadine, et al.
Publicado: (2015)

Reversible regulation of conjugation of Bacillus subtilis plasmid pLS20 by the quorum sensing peptide responsive anti-repressor Rap(pLS20)
por: Singh, Praveen K, et al.
Publicado: (2020)

Reverse crosstalk of TGFβ and PPARβ/δ signaling identified by transcriptional profiling
por: Stockert, Josefine, et al.
Publicado: (2011)

The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter
por: Barutcu, A. Rasim, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_4cnl7ve820fkhrltft4r0foebe