Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest

Several ATPases in the ATP-binding cassette F (ABCF) family confer resistance to macrolides, lincosamides and streptogramins (MLS) antibiotics. MLS are structurally distinct classes, but inhibit a common target: the peptidyl transferase (PTC) active site of the ribosome. Antibiotic resistance (ARE)...

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Detalles Bibliográficos
Autores principales: Murina, Victoriia, Kasari, Marje, Hauryliuk, Vasili, Atkinson, Gemma C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909423/
https://www.ncbi.nlm.nih.gov/pubmed/29415157
http://dx.doi.org/10.1093/nar/gky050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909423/
https://www.ncbi.nlm.nih.gov/pubmed/29415157
http://dx.doi.org/10.1093/nar/gky050

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