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Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest

Several ATPases in the ATP-binding cassette F (ABCF) family confer resistance to macrolides, lincosamides and streptogramins (MLS) antibiotics. MLS are structurally distinct classes, but inhibit a common target: the peptidyl transferase (PTC) active site of the ribosome. Antibiotic resistance (ARE)...

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Detalles Bibliográficos
Autores principales:	Murina, Victoriia, Kasari, Marje, Hauryliuk, Vasili, Atkinson, Gemma C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909423/ https://www.ncbi.nlm.nih.gov/pubmed/29415157 http://dx.doi.org/10.1093/nar/gky050

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