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Genome-wide relationship between R-loop formation and antisense transcription in Escherichia coli

Transcription termination by Rho is essential for viability in various bacteria, including some major pathogens. Since Rho acts by targeting nascent RNAs that are not simultaneously translated, it also regulates antisense transcription. Here we show that RNase H-deficient mutants of Escherichia coli...

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Detalles Bibliográficos
Autores principales: Raghunathan, Nalini, Kapshikar, Rajvardhan M, Leela, Jakku K, Mallikarjun, Jillella, Bouloc, Philippe, Gowrishankar, Jayaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909445/
https://www.ncbi.nlm.nih.gov/pubmed/29474582
http://dx.doi.org/10.1093/nar/gky118