The Sm-core mediates the retention of partially-assembled spliceosomal snRNPs in Cajal bodies until their full maturation

Cajal bodies (CBs) are nuclear non-membrane bound organelles where small nuclear ribonucleoprotein particles (snRNPs) undergo their final maturation and quality control before they are released to the nucleoplasm. However, the molecular mechanism how immature snRNPs are targeted and retained in CBs...

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Detalles Bibliográficos
Autores principales: Roithová, Adriana, Klimešová, Klára, Pánek, Josef, Will, Cindy L, Lührmann, Reinhard, Staněk, David, Girard, Cyrille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909452/
https://www.ncbi.nlm.nih.gov/pubmed/29415178
http://dx.doi.org/10.1093/nar/gky070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909452/
https://www.ncbi.nlm.nih.gov/pubmed/29415178
http://dx.doi.org/10.1093/nar/gky070

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