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G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy

G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that form within guanine-rich strands of regulatory genomic regions. G4s have been extensively described in the human genome, especially in telomeres and oncogene promoters; in recent years the presence of G4s in viruses has a...

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Detalles Bibliográficos
Autores principales: Ruggiero, Emanuela, Richter, Sara N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909458/
https://www.ncbi.nlm.nih.gov/pubmed/29554280
http://dx.doi.org/10.1093/nar/gky187