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G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy
G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that form within guanine-rich strands of regulatory genomic regions. G4s have been extensively described in the human genome, especially in telomeres and oncogene promoters; in recent years the presence of G4s in viruses has a...
Autores principales: | Ruggiero, Emanuela, Richter, Sara N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909458/ https://www.ncbi.nlm.nih.gov/pubmed/29554280 http://dx.doi.org/10.1093/nar/gky187 |
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