Genetic instability associated with loop or stem–loop structures within transcription units can be independent of nucleotide excision repair

Simple sequence repeats (SSRs) are found throughout the genome, and under some conditions can change in length over time. Germline and somatic expansions of trinucleotide repeats are associated with a series of severely disabling illnesses, including Huntington's disease. The underlying mechani...

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Detalles Bibliográficos
Autores principales: Burns, John A, Chowdhury, Moinuddin A, Cartularo, Laura, Berens, Christian, Scicchitano, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909459/
https://www.ncbi.nlm.nih.gov/pubmed/29474673
http://dx.doi.org/10.1093/nar/gky110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909459/
https://www.ncbi.nlm.nih.gov/pubmed/29474673
http://dx.doi.org/10.1093/nar/gky110

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