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Genetic instability associated with loop or stem–loop structures within transcription units can be independent of nucleotide excision repair
Simple sequence repeats (SSRs) are found throughout the genome, and under some conditions can change in length over time. Germline and somatic expansions of trinucleotide repeats are associated with a series of severely disabling illnesses, including Huntington's disease. The underlying mechani...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909459/ https://www.ncbi.nlm.nih.gov/pubmed/29474673 http://dx.doi.org/10.1093/nar/gky110 |