Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish

EZH2 is a subunit of polycomb repressive complex 2 (PRC2) that silences gene transcription via H3K27me3 and was shown to be essential for mammalian liver circadian regulation and hematopoiesis through gene silencing. Much less, however, is known about how Ezh2 acts in live zebrafish. Here, we show t...

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Detalles Bibliográficos
Autores principales: Zhong, Yingbin, Ye, Qiang, Chen, Chengyan, Wang, Mingyong, Wang, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909462/
https://www.ncbi.nlm.nih.gov/pubmed/29447387
http://dx.doi.org/10.1093/nar/gky101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909462/
https://www.ncbi.nlm.nih.gov/pubmed/29447387
http://dx.doi.org/10.1093/nar/gky101

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