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Structural analyses of NEAT1 lncRNAs suggest long-range RNA interactions that may contribute to paraspeckle architecture

Paraspeckles are nuclear bodies that regulate multiple aspects of gene expression. The long non-coding RNA (lncRNA) NEAT1 is essential for paraspeckle formation. NEAT1 has a highly ordered spatial organization within the paraspeckle, such that its 5′ and 3′ ends localize on the periphery of paraspec...

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Detalles Bibliográficos
Autores principales: Lin, Yizhu, Schmidt, Brigitte F, Bruchez, Marcel P, McManus, C Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909464/
https://www.ncbi.nlm.nih.gov/pubmed/29394378
http://dx.doi.org/10.1093/nar/gky046