Isoform-selective activity-based profiling of ERK signaling

Extracellular signal-regulated kinases (ERKs) mediate downstream signaling of RAS-RAF-MEK as key regulators of the mitogen-activated protein kinase (MAPK) pathway. Activation of ERK signaling is a hallmark of cancer and upstream MAPK proteins have been extensively pursued as drug targets for cancer...

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Detalles Bibliográficos
Autores principales: Shin, Myungsun, Franks, Caroline E., Hsu, Ku-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909473/
https://www.ncbi.nlm.nih.gov/pubmed/29732117
http://dx.doi.org/10.1039/c8sc00043c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909473/
https://www.ncbi.nlm.nih.gov/pubmed/29732117
http://dx.doi.org/10.1039/c8sc00043c

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