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Solo, a RhoA-targeting guanine nucleotide exchange factor, is critical for hemidesmosome formation and acinar development in epithelial cells

Cell-substrate adhesions are essential for various physiological processes, including embryonic development and maintenance of organ functions. Hemidesmosomes (HDs) are multiprotein complexes that attach epithelial cells to the basement membrane. Formation and remodeling of HDs are dependent on the...

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Detalles Bibliográficos
Autores principales: Fujiwara, Sachiko, Matsui, Tsubasa S., Ohashi, Kazumasa, Deguchi, Shinji, Mizuno, Kensaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909619/
https://www.ncbi.nlm.nih.gov/pubmed/29672603
http://dx.doi.org/10.1371/journal.pone.0195124