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Pharmacodynamics of the Novel Antifungal Agent F901318 for Acute Sinopulmonary Aspergillosis Caused by Aspergillus flavus

BACKGROUND: Aspergillus flavus is one of the most common agents of invasive aspergillosis and is associated with high mortality. The orotomides are a new class of antifungal agents with a novel mechanism of action. An understanding of the pharmacodynamics (PD) of the lead compound F901318 is require...

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Detalles Bibliográficos
Autores principales: Negri, Clara E, Johnson, Adam, McEntee, Laura, Box, Helen, Whalley, Sarah, Schwartz, Julie A, Ramos-Martín, V, Livermore, Joanne, Kolamunnage-Dona, Ruwanthi, Colombo, Arnaldo L, Hope, William W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909626/
https://www.ncbi.nlm.nih.gov/pubmed/28968675
http://dx.doi.org/10.1093/infdis/jix479