Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages

OBJECTIVES: We examined the in vitro pharmacodynamics and cellular accumulation of the standard anti-leishmanial drugs amphotericin B and miltefosine in intracellular Leishmania donovani amastigote–macrophage drug assays. METHODS: Primary mouse macrophages were infected with L. donovani amastigotes....

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Detalles Bibliográficos
Autores principales: Voak, Andrew A, Standing, Joseph F, Sepúlveda, Nuno, Harris, Andy, Croft, Simon L, Seifert, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909632/
https://www.ncbi.nlm.nih.gov/pubmed/29506127
http://dx.doi.org/10.1093/jac/dky014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909632/
https://www.ncbi.nlm.nih.gov/pubmed/29506127
http://dx.doi.org/10.1093/jac/dky014

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