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Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages

OBJECTIVES: We examined the in vitro pharmacodynamics and cellular accumulation of the standard anti-leishmanial drugs amphotericin B and miltefosine in intracellular Leishmania donovani amastigote–macrophage drug assays. METHODS: Primary mouse macrophages were infected with L. donovani amastigotes....

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Detalles Bibliográficos
Autores principales:	Voak, Andrew A, Standing, Joseph F, Sepúlveda, Nuno, Harris, Andy, Croft, Simon L, Seifert, Karin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909632/ https://www.ncbi.nlm.nih.gov/pubmed/29506127 http://dx.doi.org/10.1093/jac/dky014

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