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Concentration-related metabolic rate and behavioral thermoregulatory adaptations to serial administrations of nitrous oxide in rats

BACKGROUND: Initial administration of ≥60% nitrous oxide (N(2)O) to rats evokes hypothermia, but after repeated administrations the gas instead evokes hyperthermia. This sign reversal is driven mainly by increased heat production. To determine whether rats will behaviorally oppose or assist the deve...

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Detalles Bibliográficos
Autores principales: Kaiyala, Karl J., Ramsay, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909668/
https://www.ncbi.nlm.nih.gov/pubmed/29672605
http://dx.doi.org/10.1371/journal.pone.0194794