In Vivo Short-Term Topical Application of BAY 11-7082 Prevents the Acidic Bile–Induced mRNA and miRNA Oncogenic Phenotypes in Exposed Murine Hypopharyngeal Mucosa()()

PURPOSE: Bile-containing gastroesophageal reflux may promote cancer at extraesophageal sites. Acidic bile can accelerate NF-κB activation and molecular events, linked to premalignant changes in murine hypopharyngeal mucosa (HM). We hypothesize that short-term in vivo topical application of NF-κB inh...

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Detalles Bibliográficos
Autores principales: Sasaki, Clarence T., Doukas, Sotirios G., Vageli, Dimitra P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909679/
https://www.ncbi.nlm.nih.gov/pubmed/29529473
http://dx.doi.org/10.1016/j.neo.2018.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909679/
https://www.ncbi.nlm.nih.gov/pubmed/29529473
http://dx.doi.org/10.1016/j.neo.2018.02.001

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