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DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

OBJECTIVES: Systemic lupus erythematosus (SLE) is a chronic autoimmune condition with heterogeneous presentation and complex aetiology where DNA methylation changes are emerging as a contributing factor. In order to discover novel epigenetic associations and investigate their relationship to genetic...

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Detalles Bibliográficos
Autores principales: Imgenberg-Kreuz, Juliana, Carlsson Almlöf, Jonas, Leonard, Dag, Alexsson, Andrei, Nordmark, Gunnel, Eloranta, Maija-Leena, Rantapää-Dahlqvist, Solbritt, Bengtsson, Anders A, Jönsen, Andreas, Padyukov, Leonid, Gunnarsson, Iva, Svenungsson, Elisabet, Sjöwall, Christopher, Rönnblom, Lars, Syvänen, Ann-Christine, Sandling, Johanna K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909746/
https://www.ncbi.nlm.nih.gov/pubmed/29437559
http://dx.doi.org/10.1136/annrheumdis-2017-212379