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Modeling the dynamics and kinetics of HIV-1 Gag during viral assembly

We report a computational model for the assembly of HIV-1 Gag into immature viral particles at the plasma membrane. To reproduce experimental structural and kinetic properties of assembly, a process occurring on the order of minutes, a coarse-grained representation consisting of a single particle pe...

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Detalles Bibliográficos
Autores principales: Tomasini, Michael D., Johnson, Daniel S., Mincer, Joshua S., Simon, Sanford M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909904/
https://www.ncbi.nlm.nih.gov/pubmed/29677208
http://dx.doi.org/10.1371/journal.pone.0196133