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A novel statistical method for assessing effective adherence to medication and calculating optimal drug dosages

OBJECTIVE: We derive a novel model-based metric for effective adherence to medication, and validate it using data from the INhaler Compliance Assessment device (INCA(TM)). This technique employs dose timing data to estimate the threshold drug concentration needed to maintain optimal health. METHODS:...

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Detalles Bibliográficos
Autores principales: Greene, Garrett, Costello, Richard W., Cushen, Breda, Sulaiman, Imran, Mac Hale, Elaine, Conroy, Ronan M., Doyle, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909911/
https://www.ncbi.nlm.nih.gov/pubmed/29677197
http://dx.doi.org/10.1371/journal.pone.0195663