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A novel statistical method for assessing effective adherence to medication and calculating optimal drug dosages
OBJECTIVE: We derive a novel model-based metric for effective adherence to medication, and validate it using data from the INhaler Compliance Assessment device (INCA(TM)). This technique employs dose timing data to estimate the threshold drug concentration needed to maintain optimal health. METHODS:...
Autores principales: | Greene, Garrett, Costello, Richard W., Cushen, Breda, Sulaiman, Imran, Mac Hale, Elaine, Conroy, Ronan M., Doyle, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909911/ https://www.ncbi.nlm.nih.gov/pubmed/29677197 http://dx.doi.org/10.1371/journal.pone.0195663 |
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