Cargando…

Type-2 diabetic aldehyde dehydrogenase 2 mutant mice (ALDH 2*2) exhibiting heart failure with preserved ejection fraction phenotype can be determined by exercise stress echocardiography

E487K point mutation of aldehyde dehydrogenase (ALDH) 2 (ALDH2*2) in East Asians intrinsically lowers ALDH2 activity. ALDH2*2 is associated with diabetic cardiomyopathy. Diabetic patients exhibit heart failure of preserved ejection fraction (HFpEF) i.e. while the systolic heart function is preserved...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Guodong, Munukutla, Srikar, Kar, Ananya, Gardinier, Joseph, Thandavarayan, Rajarajan A., Palaniyandi, Suresh Selvaraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909916/ https://www.ncbi.nlm.nih.gov/pubmed/29677191 http://dx.doi.org/10.1371/journal.pone.0195796

Ejemplares similares

Correction: Type-2 diabetic aldehyde dehydrogenase 2 mutant mice (ALDH 2*2) exhibiting heart failure with preserved ejection fraction phenotype can be determined by exercise stress echocardiography
por: Pan, Guodong, et al.
Publicado: (2018)

ALDH2 Inhibition Potentiates High Glucose Stress-Induced Injury in Cultured Cardiomyocytes
por: Pan, Guodong, et al.
Publicado: (2016)

Aldehyde Dehydrogenase 2 Activator Augments the Beneficial Effects of Empagliflozin in Mice with Diabetes-Associated HFpEF
por: Pan, Guodong, et al.
Publicado: (2022)

Diabetic Aldehyde Dehydrogenase 2 Mutant (ALDH2*2) Mice Are More Susceptible to Cardiac Ischemic‐Reperfusion Injury Due to 4‐Hydroxy‐2‐Nonenal Induced Coronary Endothelial Cell Damage
por: Pan, Guodong, et al.
Publicado: (2021)

Cardiac Mitochondrial Respiratory Dysfunction and Tissue Damage in Chronic Hyperglycemia Correlate with Reduced Aldehyde Dehydrogenase-2 Activity
por: Mali, Vishal R., et al.
Publicado: (2016)

Sca-1+ Cells from Fetal Heart with High Aldehyde Dehydrogenase Activity Exhibit Enhanced Gene Expression for Self-Renewal, Proliferation, and Survival
por: Dey, Devaveena, et al.
Publicado: (2015)

Aldehyde Dehydrogenase 2 (ALDH2) in Rat Fatty Liver Cold Ischemia Injury
por: Panisello-Roselló, Arnau, et al.
Publicado: (2018)

Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung
por: Kuroda, Aoi, et al.
Publicado: (2017)

Aldehydes, Aldehyde Metabolism, and the ALDH2 Consortium
por: Rwere, Freeborn, et al.
Publicado: (2022)

Exposure to the Dioxin-like Pollutant PCB 126 Afflicts Coronary Endothelial Cells via Increasing 4-Hydroxy-2 Nonenal: A Role for Aldehyde Dehydrogenase 2
por: Roy, Bipradas, et al.
Publicado: (2022)

Update on the aldehyde dehydrogenase gene (ALDH) superfamily
por: Jackson, Brian, et al.
Publicado: (2011)

Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2 on blood acetaldehyde concentrations
por: Peng, Giia-Sheun, et al.
Publicado: (2009)

Aldehyde Dehydrogenase 2 (ALDH2) Genotype Affects Rectal Cancer Susceptibility Due to Alcohol Consumption
por: Matsuo, Keitaro, et al.
Publicado: (2007)

The roles of aldehyde dehydrogenases (ALDHs) in the PDH bypass of Arabidopsis
por: Wei, Yanling, et al.
Publicado: (2009)

Macrophage ALDH2 (Aldehyde Dehydrogenase 2) Stabilizing Rac2 Is Required for Efferocytosis Internalization and Reduction of Atherosclerosis Development
por: Zhang, Jian, et al.
Publicado: (2022)

The mitochondrial aldehyde dehydrogenase OsALDH2b negatively regulates tapetum degeneration in rice
por: Xie, Xianrong, et al.
Publicado: (2020)

Meta-Analysis of the Aldehyde Dehydrogenases-2 (ALDH2) Glu487Lys Polymorphism and Colorectal Cancer Risk
por: Zhao, Hua, et al.
Publicado: (2014)

The Aldehyde Dehydrogenase ALDH2*2 Allele, Associated with Alcohol Drinking Behavior, Dates Back to Prehistoric Times
por: Lin, Chih-Lang, et al.
Publicado: (2021)

Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family
por: Vasiliou, Vasilis, et al.
Publicado: (2005)

Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia
por: Sun, Xiaolei, et al.
Publicado: (2017)

Variant Aldehyde Dehydrogenase 2 (ALDH2*2) Is a Risk Factor for Coronary Spasm and ST‐Segment Elevation Myocardial Infarction
por: Mizuno, Yuji, et al.
Publicado: (2016)

Aldehyde Dehydrogenase 2 (ALDH2) Elicits Protection against Pulmonary Hypertension via Inhibition of ERK1/2-Mediated Autophagy
por: Chang, Suchi, et al.
Publicado: (2022)

Aldehyde Dehydrogenase 2 (ALDH2) Polymorphism and the Risk of Alcoholic Liver Cirrhosis among East Asians: A Meta-Analysis
por: He, Lei, et al.
Publicado: (2016)

Low Km aldehyde dehydrogenase (ALDH2) polymorphism, alcohol-drinking behavior, and chromosome alterations in peripheral lymphocytes.
por: Morimoto, K, et al.
Publicado: (1996)

The Activity of Alcohol Dehydrogenase (ADH) Isoenzymes and Aldehyde Dehydrogenase (ALDH) in the Sera of Patients with Brain Cancer
por: Jelski, Wojciech, et al.
Publicado: (2014)

Salivary Aldehyde Dehydrogenase: Activity towards Aromatic Aldehydes and Comparison with Recombinant ALDH3A1
por: Giebułtowicz, Joanna, et al.
Publicado: (2009)

Associations between aldehyde dehydrogenase 2 (ALDH2) rs671 genetic polymorphisms, lifestyles and hypertension risk in Chinese Han people
por: Ma, Cong, et al.
Publicado: (2017)

Genetic Polymorphisms of the Mitochondrial Aldehyde Dehydrogenase ALDH2 Gene in a Large Ethnic Hakka Population in Southern China
por: Zhong, Zhixiong, et al.
Publicado: (2018)

Genome-Wide Identification and Analysis of Grape Aldehyde Dehydrogenase (ALDH) Gene Superfamily
por: Zhang, Yucheng, et al.
Publicado: (2012)

Mining distinct aldehyde dehydrogenase 1 (ALDH1) isoenzymes in gastric cancer
por: Shen, Jia-Xin, et al.
Publicado: (2016)

Comprehensive Analysis of Aldehyde Dehydrogenases (ALDHs) and Its Significant Role in Hepatocellular Carcinoma
por: Yao, Senbang, et al.
Publicado: (2021)

Aldehyde Dehydrogenase 2 Family Member (ALDH2) Is a Therapeutic Index for Oxaliplatin Response on Colorectal Cancer Therapy with Dysfunction p53
por: Wang, Wei-Lin, et al.
Publicado: (2022)

Long Noncoding RNA SNHG16 Regulates the Growth of Human Lung Cancer Cells by Modulating the Expression of Aldehyde Dehydrogenase 2 (ALDH2)
por: Li, Yan, et al.
Publicado: (2022)

SARS–CoV-2 Mediated Hyperferritinemia and Cardiac Arrest: Preliminary Insights
por: VasanthiDharmalingam, Prakash, et al.
Publicado: (2021)

3′UTR shortening of profibrotic genes and reversibility of fibrosis in patients with end‐stage right ventricular failure
por: Neupane, Rahul, et al.
Publicado: (2022)

Acetylation of aldehyde dehydrogenase ALDH1L2 regulates cellular redox balance and the chemosensitivity of colorectal cancer to 5-fluorouracil
por: Li, Chaoqun, et al.
Publicado: (2023)

Overexpression of the Aldehyde Dehydrogenase Gene ZmALDH Confers Aluminum Tolerance in Arabidopsis thaliana
por: Du, Han-Mei, et al.
Publicado: (2022)

The diagnostic value of alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) measurement in the sera of patients with brain tumor
por: Jelski, Wojciech, et al.
Publicado: (2017)

Aldehyde Dehydrogenase 2 (ALDH2) Glu504Lys Polymorphism Affects Collateral Circulation and Short-Term Prognosis of Acute Cerebral Infarction Patients
por: Qu, Yun, et al.
Publicado: (2017)

Variant Aldehyde Dehydrogenase 2 (ALDH2*2) as a Risk Factor for Mechanical LA Substrate Formation and Atrial Fibrillation with Modest Alcohol Consumption in Ethnic Asians
por: Hung, Chung-Lieh, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6tcvvr5jsj6r9fkckrn2tahhsn