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Salt bridges gate α-catenin activation at intercellular junctions
Cadherin complexes transduce force fluctuations at junctions to activate signals that reinforce stressed intercellular contacts. α-Catenin is an identified force transducer within cadherin complexes that is autoinhibited under low tension. Increased force triggers a conformational change that expose...
Autores principales: | Barrick, Samantha, Li, Jing, Kong, Xinyu, Ray, Alokananda, Tajkhorshid, Emad, Leckband, Deborah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909925/ https://www.ncbi.nlm.nih.gov/pubmed/29142072 http://dx.doi.org/10.1091/mbc.E17-03-0168 |
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