GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production

The diversion of the membrane-bound β-site amyloid precursor protein–(APP) cleaving enzyme (BACE1) from the endolysosomal pathway to recycling endosomes represents an important transport step in the regulation of amyloid beta (Aβ) production. However, the mechanisms that regulate endosome sorting of...

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Detalles Bibliográficos
Autores principales: Toh, Wei Hong, Chia, Pei Zhi Cheryl, Hossain, Mohammed Iqbal, Gleeson, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909931/
https://www.ncbi.nlm.nih.gov/pubmed/29142073
http://dx.doi.org/10.1091/mbc.E17-05-0270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909931/
https://www.ncbi.nlm.nih.gov/pubmed/29142073
http://dx.doi.org/10.1091/mbc.E17-05-0270

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