STAT3 controls COL1A2 enhancer activation cooperatively with JunB, regulates type I collagen synthesis posttranscriptionally, and is essential for lung myofibroblast differentiation

Fibroblast differentiation is a key cellular process that underlies the process of fibrosis, a deadly complication of fibrotic diseases like scleroderma (SSc). This transition coincides with the overproduction of collagen type I (COL1) and other extracellular matrix proteins. High-level expression o...

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Detalles Bibliográficos
Autores principales: Papaioannou, Ioannis, Xu, Shiwen, Denton, Christopher P., Abraham, David J., Ponticos, Markella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909935/
https://www.ncbi.nlm.nih.gov/pubmed/29142074
http://dx.doi.org/10.1091/mbc.E17-06-0342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909935/
https://www.ncbi.nlm.nih.gov/pubmed/29142074
http://dx.doi.org/10.1091/mbc.E17-06-0342

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