An Essential Role for ECSIT in Mitochondrial Complex I Assembly and Mitophagy in Macrophages

ECSIT is a mitochondrial complex I (CI)-associated protein that has been shown to regulate the production of mitochondrial reactive oxygen species (mROS) following engagement of Toll-like receptors (TLRs). We have generated an Ecsit conditional knockout (CKO) mouse strain to study the in vivo role o...

Descripción completa

Detalles Bibliográficos
Autores principales: Carneiro, Flávia R.G., Lepelley, Alice, Seeley, John J., Hayden, Matthew S., Ghosh, Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909989/
https://www.ncbi.nlm.nih.gov/pubmed/29514094
http://dx.doi.org/10.1016/j.celrep.2018.02.051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909989/
https://www.ncbi.nlm.nih.gov/pubmed/29514094
http://dx.doi.org/10.1016/j.celrep.2018.02.051

Ejemplares similares