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An Essential Role for ECSIT in Mitochondrial Complex I Assembly and Mitophagy in Macrophages

ECSIT is a mitochondrial complex I (CI)-associated protein that has been shown to regulate the production of mitochondrial reactive oxygen species (mROS) following engagement of Toll-like receptors (TLRs). We have generated an Ecsit conditional knockout (CKO) mouse strain to study the in vivo role o...

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Detalles Bibliográficos
Autores principales:	Carneiro, Flávia R.G., Lepelley, Alice, Seeley, John J., Hayden, Matthew S., Ghosh, Sankar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909989/ https://www.ncbi.nlm.nih.gov/pubmed/29514094 http://dx.doi.org/10.1016/j.celrep.2018.02.051

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