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Single Cell mRNA Cytometry via Sequence-Specific Nanoparticle Clustering and Trapping

Cell-to-cell variation in gene expression creates a need for techniques that characterize expression at the level of individual cells. This is particularly true for rare circulating tumor cells (CTCs), in which subtyping and drug resistance are of intense interest. Here we describe a method for cell...

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Detalles Bibliográficos
Autores principales: Labib, Mahmoud, Mohamadi, Reza M., Poudineh, Mahla, Ahmed, Sharif U., Ivanov, Ivaylo, Huang, Ching-Lung, Moosavi, Maral, Sargent, Edward H., Kelley, Shana O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910253/
https://www.ncbi.nlm.nih.gov/pubmed/29610463
http://dx.doi.org/10.1038/s41557-018-0025-8