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Chimeric protein identification of dystrophic, Pierson and other laminin polymerization residues
Laminin polymerization is a key step of basement membrane self-assembly that depends on the binding of the three different N-terminal globular LN domains. Several mutations in the LN domains cause LAMA2-deficient muscular dystrophy and LAMB2-deficient Pierson syndrome. These mutations may affect pol...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910262/ https://www.ncbi.nlm.nih.gov/pubmed/29408412 http://dx.doi.org/10.1016/j.matbio.2018.01.012 |