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Mass spectrometry analysis reveals differences in the host cell protein species found in pseudotyped lentiviral vectors

Lentiviral vectors (LVs) have been successfully used in clinical trials showing long term therapeutic benefits. Studying the role of cellular proteins in lentivirus HIV-1 life cycle can help understand virus assembly and budding, leading to improvement of LV production for gene therapy. Lentiviral v...

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Detalles Bibliográficos
Autores principales: Johnson, Sabine, Wheeler, Jun X., Thorpe, Robin, Collins, Mary, Takeuchi, Yasuhiro, Zhao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910304/
https://www.ncbi.nlm.nih.gov/pubmed/29361371
http://dx.doi.org/10.1016/j.biologicals.2017.12.005