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Mechanically interlocked functionalization of monoclonal antibodies

Because monoclonal antibodies (mAbs) have exceptional specificity and favorable pharmacology, substantial efforts have been made to functionalize them, either with potent cytotoxins, biologics, radionuclides, or fluorescent groups for therapeutic benefit and/or use as theranostic agents. To exploit...

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Detalles Bibliográficos
Autores principales: Bzymek, Krzysztof P., Puckett, James W., Zer, Cindy, Xie, Jun, Ma, Yuelong, King, Jeremy D., Goodstein, Leah H., Avery, Kendra N., Colcher, David, Singh, Gagandeep, Horne, David A., Williams, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910394/
https://www.ncbi.nlm.nih.gov/pubmed/29679060
http://dx.doi.org/10.1038/s41467-018-03976-5