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Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets
Both CC and CXC-class chemokines drive inflammatory disease. Tick salivary chemokine-binding proteins (CKBPs), or evasins, specifically bind subsets of CC- or CXC-chemokines, and could precisely target disease-relevant chemokines. Here we have used yeast surface display to identify two tick evasins:...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910400/ https://www.ncbi.nlm.nih.gov/pubmed/29679010 http://dx.doi.org/10.1038/s41598-018-24568-9 |