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The transcription-repair coupling factor Mfd associates with RNA polymerase in the absence of exogenous damage

During transcription elongation, bacterial RNA polymerase (RNAP) can pause, backtrack or stall when transcribing template DNA. Stalled transcription elongation complexes at sites of bulky lesions can be rescued by the transcription terminator Mfd. The molecular mechanisms of Mfd recruitment to trans...

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Detalles Bibliográficos
Autores principales: Ho, Han N., van Oijen, Antoine M., Ghodke, Harshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910403/
https://www.ncbi.nlm.nih.gov/pubmed/29679003
http://dx.doi.org/10.1038/s41467-018-03790-z