Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction

The demand for highly efficient macromolecular drugs, used in the treatment of many severe diseases, is continuously increasing. However, the hydrophilic character and large molecular size of these drugs significantly limit their ability to permeate across cellular membranes and thus impede the drug...

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Detalles Bibliográficos
Autores principales: Hedegaard, Sofie Fogh, Derbas, Mohammed Sobhi, Lind, Tania Kjellerup, Kasimova, Marina Robertnova, Christensen, Malene Vinther, Michaelsen, Maria Høtoft, Campbell, Richard A., Jorgensen, Lene, Franzyk, Henrik, Cárdenas, Marité, Nielsen, Hanne Mørck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910404/
https://www.ncbi.nlm.nih.gov/pubmed/29679078
http://dx.doi.org/10.1038/s41598-018-24154-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910404/
https://www.ncbi.nlm.nih.gov/pubmed/29679078
http://dx.doi.org/10.1038/s41598-018-24154-z

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