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MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression

Precise mitotic spindle orientation is essential for both cell fate and tissue organization while defects in this process are associated with tumorigenesis and other diseases. In most animal cell types, the dynein motor complex is anchored at the cell cortex and exerts pulling forces on astral micro...

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Detalles Bibliográficos
Autores principales: Vodicska, Barbara, Cerikan, Berati, Schiebel, Elmar, Hoffmann, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910412/
https://www.ncbi.nlm.nih.gov/pubmed/29679050
http://dx.doi.org/10.1038/s41598-018-24682-8