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Disruption of Hox9,10,11 function results in cellular level lineage infidelity in the kidney
Hox genes are important regulators of development. The 39 mammalian Hox genes have considerable functional overlap, greatly confounding their study. In this report, we generated mice with multiple combinations of paralogous and flanking Abd-B Hox gene mutations to investigate functional redundancies...
Autores principales: | Drake, Keri A., Adam, Mike, Mahoney, Robert, Potter, S. Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910417/ https://www.ncbi.nlm.nih.gov/pubmed/29679048 http://dx.doi.org/10.1038/s41598-018-24782-5 |
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