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Self-replication of DNA by its encoded proteins in liposome-based synthetic cells

Replication of DNA-encoded information and its conversion into functional proteins are universal properties of life. In an effort toward the construction of a synthetic minimal cell, we implement here the DNA replication machinery of the Φ29 virus in a cell-free gene expression system. Amplification...

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Detalles Bibliográficos
Autores principales: van Nies, Pauline, Westerlaken, Ilja, Blanken, Duco, Salas, Margarita, Mencía, Mario, Danelon, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910420/
https://www.ncbi.nlm.nih.gov/pubmed/29679002
http://dx.doi.org/10.1038/s41467-018-03926-1