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NFκB activation in differentiating glioblastoma stem-like cells is promoted by hyaluronic acid signaling through TLR4

We have previously described that the NFκB pathway is upregulated during differentiation of glioblastoma stem-like cells (GSCs) which keeps differentiating GSCs in a proliferative astrocytic precursor state. However, extracellular signals and cellular mediators of this pathway are not clear yet. Her...

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Detalles Bibliográficos
Autores principales: Ferrandez, Eva, Gutierrez, Olga, Segundo, David San, Fernandez-Luna, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910430/
https://www.ncbi.nlm.nih.gov/pubmed/29679017
http://dx.doi.org/10.1038/s41598-018-24444-6